Standard

Neonatal circulating Complement Component 3 (C3) protein concentration

WHR1 · rs114492815

What the study found

Who was studied 68,768 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.14 higher (95% confidence interval 0.12-0.16); p = 2 × 10−23.

Where it sits Chromosome 6, band 6p21.33 — in an intron of WHR1.

What each result means

C/C No copy of the version the research linked to Neonatal circulating Complement Component 3 (C3) protein concentration. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Neonatal circulating Complement Component 3 (C3) protein concentration. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Neonatal circulating Complement Component 3 (C3) protein concentration. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs114492815

What is rs114492815?

rs114492815 is a single position in the genome, in or near the WHR1 gene. Published research associates it with neonatal circulating complement component 3 (c3) protein concentration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs114492815 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs114492815 come from?

GWAS Catalog, Cell genomics 2023, PMID:38116117. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Neonatal circulating Complement Component 3 (C3) protein concentration (rs114492815). MyGeneLog™. https://www.mygenelog.com/variants/rs114492815

← See all variants