Standard

Systolic blood pressure (MTAG)

near KRT18P9 · rs114472600

Where this position leads

Condition: Blood Pressure

rs114472600 Condition: Blood Pressure Blood Pressure Condition rs114472600 rs114472600 near KRT18P9

What the study found

Who was studied at least 757,601 European ancestry individuals (MTAG boosted by 455,258 Alzheimer's disease samples).

The effect Each copy of the C allele shifted the measure 0.025 higher (95% confidence interval 0.017-0.033); p = 2 × 10−9.

Where it sits Chromosome 6, band 6p21.31 — between genes, 7.7 kb from KRT18P9.

What each result means

C/C Two copies of the version the research linked to Systolic blood pressure (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Systolic blood pressure (MTAG). That is a smaller link than two copies.
T/T No copy of the version the research linked to Systolic blood pressure (MTAG). This is the starting point the study compared everyone against.
Source

Questions about rs114472600

What is rs114472600?

rs114472600 is a single position in the genome, in or near the near KRT18P9 gene. Published research associates it with systolic blood pressure (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs114472600 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs114472600 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs114472600 come from?

GWAS Catalog, Nature communications 2024, PMID:39537608. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Systolic blood pressure (MTAG) (rs114472600). MyGeneLog™. https://www.mygenelog.com/variants/rs114472600

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