Sensitive

Schizophrenia

OR12D3 · rs114071887

Where this position leads

Condition: Schizophrenia

rs114071887 Condition: Schizophrenia Schizophrenia Condition rs114071887 rs114071887 OR12D3

What the study found

Who was studied 14,023 East Asian ancestry cases, 33,640 European ancestry cases, 31,505 East Asian ancestry controls, 43,456 European ancestry controls.

The effect Each copy of the G allele carried 1.24 times the odds of Schizophrenia (95% confidence interval 1.2-1.28); p = 7 × 10−25.

Where it sits Chromosome 6, band 6p22.1 — a missense change in OR5V1.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Schizophrenia — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Schizophrenia.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Schizophrenia compared to the general population.
Source

Questions about rs114071887

What is rs114071887?

rs114071887 is a single position in the genome, in or near the OR12D3 gene. Published research associates it with schizophrenia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs114071887 linked to?

On MyGeneLog this position is linked to Schizophrenia. The research behind each link, and its sources, are set out on that condition page.

Does having rs114071887 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs114071887 come from?

GWAS Catalog, Schizophr Bull 2018, PMID:30285260. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Schizophrenia (rs114071887). MyGeneLog™. https://www.mygenelog.com/variants/rs114071887

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