Standard

Myositis

DDX39B · rs114050967

Where this position leads

Condition: Myositis

rs114050967 Condition: Myositis Myositis Condition rs114050967 rs114050967 DDX39B

What the study found

Who was studied 1,710 European ancestry cases, 4,724 European ancestry controls.

The effect Each copy of the G allele carried 2.32 times the odds of Myositis; p = 3 × 10−49.

Where it sits Chromosome 6, band 6p21.33 — in an intron of DDX39B.

What each result means

A/A No copy of the version the research linked to Myositis. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Myositis. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Myositis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs114050967

What is rs114050967?

rs114050967 is a single position in the genome, in or near the DDX39B gene. Published research associates it with myositis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs114050967 linked to?

On MyGeneLog this position is linked to Myositis. The research behind each link, and its sources, are set out on that condition page.

Does having rs114050967 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs114050967 come from?

GWAS Catalog, Genes Immun 2015, PMID:26291516. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Myositis (rs114050967). MyGeneLog™. https://www.mygenelog.com/variants/rs114050967

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