Standard
Myositis
DDX39B · rs114050967
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype with typical/baseline likelihood of Myositis — no copies of the reported risk allele.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Myositis.
G/G
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Myositis compared to the general population.
Source
Genome-wide association study identifies HLA 8.1 ancestral haplotype alleles as major genetic risk factors for myositis phenotypes
Miller FW,
Chen W,
O'Hanlon TP,
Cooper RG,
Vencovsky J,
Rider LG,
Danko K,
Wedderburn LR,
Lundberg IE,
Pachman LM,
Reed AM,
Ytterberg SR
and 13 more — show all
Padyukov L,
Selva-O'Callaghan A,
Radstake TR,
Isenberg DA,
Chinoy H,
Ollier WE,
Scheet P,
Peng B,
Lee A,
Byun J,
Lamb JA,
Gregersen PK,
Amos CI
Genes and immunity · 2015 · PMID 26291516
Questions about rs114050967
What is rs114050967?
rs114050967 is a single position in the genome, in or near the DDX39B gene. Published research associates it with myositis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs114050967 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs114050967 come from?
GWAS Catalog, Genes Immun 2015, PMID:26291516. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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