0 132218Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others8Total13Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 2,201 African American cases, 159,861 African American controls.
The effect
Each copy of the A allele carried 0.67 times the odds of Sarcoidosis (95% confidence interval 0.62-0.72); p = 1 × 10−27.
How common The A allele had a frequency of about 73% in the people studied.
Where it sits Chromosome 6, band 6p21.32 — a synonymous change in HLA-DQB1.
What each result means
A/ATwo copies of the version the research linked to Sarcoidosis. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Sarcoidosis. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Sarcoidosis. This is the starting point the study compared everyone against.
Nature communications · 2025 · PMID 40075078 · open access
Questions about rs1140310
What is rs1140310?
rs1140310 is a single position in the genome, in or near the HLA-DQB1 gene. Published research associates it with sarcoidosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1140310 linked to?
On MyGeneLog this position is linked to Sarcoidosis. The research behind each link, and its sources, are set out on that condition page.
Does having rs1140310 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1140310 come from?
GWAS Catalog, Nature communications 2025, PMID:40075078. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 132218Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others8Total13Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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