0 4112Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon1Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 140,025 European ancestry cases, 344,349 European ancestry controls, 140,025 South Asian ancestry cases, 344,349 South Asian ancestry controls, 140,025 East Asian ancestry cases, 344,349 East Asian ancestry controls, 140,025 African ancestry cases, 344,349 African ancestry controls, 140,025 Hispanic or Latin American cases, 344,349 Hispanic or Latin American controls.
The effect
Each copy of the T allele carried 0.99 times the odds of Osteoarthritis (95% confidence interval 0.99-0.99); p = 2 × 10−10.
How common The T allele had a frequency of about 80% in the people studied.
Where it sits Chromosome 7, band 7p22.1 — in an intron of DAGLB.
What each result means
C/CNo copy of the version the research linked to Osteoarthritis. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Osteoarthritis. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Osteoarthritis. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs113907280 is a single position in the genome, in or near the DAGLB gene. Published research associates it with osteoarthritis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs113907280 linked to?
On MyGeneLog this position is linked to Knee Osteoarthritis. The research behind each link, and its sources, are set out on that condition page.
Does having rs113907280 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs113907280 come from?
GWAS Catalog, Nature genetics 2022, PMID:36411363. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 4112Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon1Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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