Sensitive

Bipolar disorder or major depressive disorder

TUBGCP6 · rs113872034

Where this position leads

Condition: Major Depressive Disorder

rs113872034 Condition: Major Depressive Disorder Major Depressive Disorder Condition rs113872034 rs113872034 TUBGCP6

What the study found

Who was studied 164,933 European ancestry major depressive disorder cases, 20,352 European ancestry bipolar disorder cases, 439,741 European ancestry controls.

The effect The reported allele is G; the catalogue records no effect size ; p = 1 × 10−9.

Where it sits Chromosome 22, band 22q13.33 — in an intron of TUBGCP6.

What each result means

A/A No copy of the version the research linked to Bipolar disorder or major depressive disorder. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Bipolar disorder or major depressive disorder. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Bipolar disorder or major depressive disorder. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs113872034

What is rs113872034?

rs113872034 is a single position in the genome, in or near the TUBGCP6 gene. Published research associates it with bipolar disorder or major depressive disorder. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs113872034 linked to?

On MyGeneLog this position is linked to Major Depressive Disorder. The research behind each link, and its sources, are set out on that condition page.

Does having rs113872034 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs113872034 come from?

GWAS Catalog, Biological psychiatry 2020, PMID:31926635. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Bipolar disorder or major depressive disorder (rs113872034). MyGeneLog™. https://www.mygenelog.com/variants/rs113872034

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