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Who was studied 44,383 European ancestry cases, 260,715 European ancestry controls; replicated in 4,854 European ancestry cases, 33,806 European ancestry controls, 998 Caribbean ancestry cases, 5,835 Caribbean ancestry controls, 3,368 East Asian ancestry cases, 191,045 East Asian ancestry controls.
The effect
Each copy of the A allele carried 1.65 times the odds of Asthma in muscoskeletal disease (95% confidence interval 1.48-1.81); p = 2 × 10−9.
How common The A allele had a frequency of about 2% in the people studied.
Where it sits Chromosome 17, band 17p12 — in an intron of COX10-DT.
What each result means
A/ATwo copies of the version the research linked to Asthma in muscoskeletal disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Asthma in muscoskeletal disease. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Asthma in muscoskeletal disease. This is the starting point the study compared everyone against.
Nature communications · 2022 · PMID 36344522 · open access
Questions about rs113757163
What is rs113757163?
rs113757163 is a single position in the genome, in or near the COX10-DT gene. Published research associates it with asthma in muscoskeletal disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs113757163 linked to?
On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.
Does having rs113757163 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs113757163 come from?
GWAS Catalog, Nature communications 2022, PMID:36344522. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Asthma in muscoskeletal disease (rs113757163). MyGeneLog™. https://www.mygenelog.com/variants/rs113757163