Sensitive

Childhood onset type 2 diabetes

SLC16A11 · rs113748381

Where this position leads

Condition: Type 2 Diabetes

rs113748381 Condition: Type 2 Diabetes Type 2 Diabetes Condition rs113748381 rs113748381 SLC16A11

What the study found

Who was studied 664 European ancestry youth cases, 1,068 African American youth cases, 1,274 Hispanic youth cases, 1,434 European ancestry adult controls, 1,068 African American adult controls, 3,559 Hispanic adult controls.

The effect Each copy of the A allele carried 1.04 times the odds of Childhood onset type 2 diabetes; p = 4 × 10−8.

Where it sits Chromosome 17, band 17p13.1 — between genes, 5.7 kb from SLC16A11.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Childhood onset type 2 diabetes compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Childhood onset type 2 diabetes.
G/G Published research associates this genotype with typical/baseline likelihood of Childhood onset type 2 diabetes — no copies of the reported risk allele.
Source

Questions about rs113748381

What is rs113748381?

rs113748381 is a single position in the genome, in or near the SLC16A11 gene. Published research associates it with childhood onset type 2 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs113748381 linked to?

On MyGeneLog this position is linked to Type 2 Diabetes. The research behind each link, and its sources, are set out on that condition page.

Does having rs113748381 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs113748381 come from?

GWAS Catalog, Diabetes 2021, PMID:33479058. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Childhood onset type 2 diabetes (rs113748381). MyGeneLog™. https://www.mygenelog.com/variants/rs113748381

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