Sensitive
AR-C124910XX levels in individuals with acute coronary syndromes treated with ticagrelor
SLCO1A2 · rs113681054
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype with typical/baseline likelihood of AR-C124910XX levels in individuals with acute coronary syndromes treated with ticagrelor — no copies of the reported risk allele. (GWAS Catalog, Eur Heart J 2015, PMID:25935875)
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with AR-C124910XX levels in individuals with acute coronary syndromes treated with ticagrelor. (GWAS Catalog, Eur Heart J 2015, PMID:25935875)
T/T
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of AR-C124910XX levels in individuals with acute coronary syndromes treated with ticagrelor compared to the general population. (GWAS Catalog, Eur Heart J 2015, PMID:25935875)
Source
Effect of genetic variations on ticagrelor plasma levels and clinical outcomes
Varenhorst C,
Eriksson N,
Johansson Å,
Barratt BJ,
Hagström E,
Åkerblom A,
Syvänen AC,
Becker RC,
James SK,
Katus HA,
Husted S,
Steg PG
and 5 more — show all
European heart journal · 2015 · PMID 25935875
Questions about rs113681054
What is rs113681054?
rs113681054 is a single position in the genome, in or near the SLCO1A2 gene. Published research associates it with ar-c124910xx levels in individuals with acute coronary syndromes treated with ticagrelor. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs113681054 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs113681054 come from?
GWAS Catalog, Eur Heart J 2015, PMID:25935875. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants