Standard

Cluster headache

LINC01877 · rs113658130

Where this position leads

Condition: Headache

rs113658130 Condition: Headache Headache Condition rs113658130 rs113658130 LINC01877

What the study found

Who was studied 1,443 European ancestry cases, 6,748 European ancestry controls.

The effect Each copy of the C allele carried 1.51 times the odds of Cluster headache (95% confidence interval 1.27-1.66); p = 2 × 10−17.

How common The C allele had a frequency of about 69% in the people studied.

Where it sits Chromosome 2, band 2q33.1 — in an intron of LINC01877.

What each result means

C/C Two copies of the version the research linked to Cluster headache. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Cluster headache. That is a smaller link than two copies.
T/T No copy of the version the research linked to Cluster headache. This is the starting point the study compared everyone against.
Source

Questions about rs113658130

What is rs113658130?

rs113658130 is a single position in the genome, in or near the LINC01877 gene. Published research associates it with cluster headache. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs113658130 linked to?

On MyGeneLog this position is linked to Headache. The research behind each link, and its sources, are set out on that condition page.

Does having rs113658130 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs113658130 come from?

GWAS Catalog, Annals of neurology 2021, PMID:34184781. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Cluster headache (rs113658130). MyGeneLog™. https://www.mygenelog.com/variants/rs113658130

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