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IL34 protein levels

ST3GAL2 · rs113615933

Where this position leads

Condition: Celiac Disease

rs113615933 Condition: Celiac Disease Celiac Disease Condition rs113615933 rs113615933 ST3GAL2

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.223 higher (95% confidence interval 0.15-0.29); p = 6 × 10−12.

How common The T allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 16, band 16q22.1 — in an intron of ST3GAL2.

What each result means

C/C No copy of the version the research linked to IL34 protein levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to IL34 protein levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to IL34 protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs113615933

What is rs113615933?

rs113615933 is a single position in the genome, in or near the ST3GAL2 gene. Published research associates it with il34 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs113615933 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs113615933 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs113615933 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

IL34 protein levels (rs113615933). MyGeneLog™. https://www.mygenelog.com/variants/rs113615933

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