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Who was studied 305 Turkish ancestry cases, 106 European ancestry cases, 483 Turkish ancestry controls, 553 European ancestry controls.
The effect
The reported allele is T; the catalogue records no effect size
; p = 4 × 10−9.
How common The T allele had a frequency of about 9% in the people studied.
Where it sits Chromosome 6, band 6p21.32 — between genes, 1 kb from HLA-DQB1.
What each result means
G/GNo copy of the version the research linked to Takayasu arteritis. This is the starting point the study compared everyone against.
G/TOne copy of the version the research linked to Takayasu arteritis. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Takayasu arteritis. That is the strongest link of the three results. A link in a study is not a diagnosis.
American journal of human genetics · 2013 · PMID 23830517
Questions about rs113452171
What is rs113452171?
rs113452171 is a single position in the genome, in or near the HLA-DQB1 gene. Published research associates it with takayasu arteritis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs113452171 linked to?
On MyGeneLog this position is linked to Takayasu Arteritis. The research behind each link, and its sources, are set out on that condition page.
Does having rs113452171 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs113452171 come from?
GWAS Catalog, Am J Hum Genet 2013, PMID:23830517. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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