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Age at menopause

COPG1 · rs113430717

Where this position leads

Condition: Age at Menopause

rs113430717 Condition: Age at Menopause Age at Menopause Condition rs113430717 rs113430717 COPG1

What the study found

Who was studied 10,041 Chinese ancestry females; replicated in 1,602 Chinese ancestry females.

The effect Each copy of the A allele shifted the measure 0.629 lower; p = 6 × 10−15.

How common The A allele had a frequency of about 12% in the people studied.

Where it sits Chromosome 3, band 3q21.3 — in an intron of COPG1.

What each result means

A/A Two copies of the version the research linked to Age at menopause. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Age at menopause. That is a smaller link than two copies.
T/T No copy of the version the research linked to Age at menopause. This is the starting point the study compared everyone against.
Source

Questions about rs113430717

What is rs113430717?

rs113430717 is a single position in the genome, in or near the COPG1 gene. Published research associates it with age at menopause. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs113430717 linked to?

On MyGeneLog this position is linked to Age at Menopause. The research behind each link, and its sources, are set out on that condition page.

Does having rs113430717 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs113430717 come from?

GWAS Catalog, Human reproduction (Oxford, England) 2022, PMID:35413122. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Age at menopause (rs113430717). MyGeneLog™. https://www.mygenelog.com/variants/rs113430717

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