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Branched-chain, straight-chain, or cyclopropyl 12:1 fatty acid levels

ACOT2 · rs113425878

What the study found

Who was studied 8,256 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.234 lower (95% confidence interval 0.17-0.3); p = 2 × 10−12.

How common The G allele had a frequency of about 5% in the people studied.

Where it sits Chromosome 14, band 14q24.3 — in an intron of ACOT2.

What each result means

C/C No copy of the version the research linked to Branched-chain, straight-chain, or cyclopropyl 12:1 fatty acid levels. This is the starting point the study compared everyone against.
C/G One copy of the version the research linked to Branched-chain, straight-chain, or cyclopropyl 12:1 fatty acid levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Branched-chain, straight-chain, or cyclopropyl 12:1 fatty acid levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs113425878

What is rs113425878?

rs113425878 is a single position in the genome, in or near the ACOT2 gene. Published research associates it with branched-chain, straight-chain, or cyclopropyl 12:1 fatty acid levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs113425878 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs113425878 come from?

GWAS Catalog, Nature genetics 2023, PMID:36635386. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Branched-chain, straight-chain, or cyclopropyl 12:1 fatty acid levels (rs113425878). MyGeneLog™. https://www.mygenelog.com/variants/rs113425878

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