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Who was studied 119,012 African American or Afro-Caribbean individuals, 57,810 Hispanic or Latin American individuals, 6,384 East Asian ancestry individuals, 424,306 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0469 lower (95% confidence interval 0.035-0.059); p = 5 × 10−15.
How common The G allele had a frequency of about 88% in the people studied.
Where it sits Chromosome 3, band 3p22.2 — in an intron of PLCD1.
What ClinVar records
ClassificationBenign; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 2 submitters), last evaluated 2021-06-20.
ClinVar record 1244332NM_006225.4(PLCD1):c.1724-32C>T
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
A/ANo copy of the version the research linked to height (minimum, inv-normal transformed). This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to height (minimum, inv-normal transformed). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to height (minimum, inv-normal transformed). That is the strongest link of the three results. A link in a study is not a diagnosis.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs113213588
What is rs113213588?
rs113213588 is a single position in the genome, in or near the PLCD1 gene. Published research associates it with height (minimum, inv-normal transformed). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs113213588 linked to?
On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.
Does having rs113213588 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs113213588 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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