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Total concentration of 19 human milk oligosaccharides

SULT2B1 · rs1132054

What the study found

Who was studied 764 European ancestry individuals, 48 South Asian ancestry individuals, 126 East Asian ancestry individuals, 26 African American or Afro-Caribbean individuals, 16 Other admixed ancestry and unknown ancestry individuals; replicated in 395 individuals.

The effect Each copy of the T allele shifted the measure 8.05 zscore lower; p = 8 × 10−16.

Where it sits Chromosome 19, band 19q13.33 — a synonymous change in SULT2B1.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Total concentration of 19 human milk oligosaccharides — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Total concentration of 19 human milk oligosaccharides.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Total concentration of 19 human milk oligosaccharides compared to the general population.
Source

Questions about rs1132054

What is rs1132054?

rs1132054 is a single position in the genome, in or near the SULT2B1 gene. Published research associates it with total concentration of 19 human milk oligosaccharides. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1132054 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1132054 come from?

GWAS Catalog, Nature communications 2024, PMID:39232002. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Total concentration of 19 human milk oligosaccharides (rs1132054). MyGeneLog™. https://www.mygenelog.com/variants/rs1132054

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