Sensitive

COMM domain-containing protein 10 level in Chronic kidney disease with hypertension and no diabetes (23257_14)

COMMD10 · rs1129495

What the study found

Who was studied 466 African American individuals.

The effect Each copy of the G allele shifted the measure 1.26 lower (95% confidence interval 1.16-1.36); p = 1 × 10−138.

How common The G allele had a frequency of about 23% in the people studied.

Where it sits Chromosome 5, band 5q23.1 — a missense change in COMMD10.

What each result means

G/G Two copies of the version the research linked to COMM domain-containing protein 10 level in Chronic kidney disease with hypertension and no diabetes (23257_14). That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to COMM domain-containing protein 10 level in Chronic kidney disease with hypertension and no diabetes (23257_14). That is a smaller link than two copies.
T/T No copy of the version the research linked to COMM domain-containing protein 10 level in Chronic kidney disease with hypertension and no diabetes (23257_14). This is the starting point the study compared everyone against.
Source

Questions about rs1129495

What is rs1129495?

rs1129495 is a single position in the genome, in or near the COMMD10 gene. Published research associates it with comm domain-containing protein 10 level in chronic kidney disease with hypertension and no diabetes (23257_14). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1129495 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1129495 come from?

GWAS Catalog, Kidney international 2022, PMID:35870639. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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COMM domain-containing protein 10 level in Chronic kidney disease with hypertension and no diabetes (23257_14) (rs1129495). MyGeneLog™. https://www.mygenelog.com/variants/rs1129495

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