Standard

Eosinophil count

IKZF3 · rs112876941

What the study found

Who was studied 365,954 British ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.07 lower (95% confidence interval 0.05-0.09); p = 3 × 10−12.

How common The T allele had a frequency of about 39% in the people studied.

Where it sits Chromosome 17, band 17q12 — in an intron of IKZF3.

What each result means

A/A No copy of the version the research linked to Eosinophil count. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Eosinophil count. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Eosinophil count. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs112876941

What is rs112876941?

rs112876941 is a single position in the genome, in or near the IKZF3 gene. Published research associates it with eosinophil count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs112876941 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs112876941 come from?

GWAS Catalog, Frontiers in immunology 2022, PMID:35935937. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Eosinophil count (rs112876941). MyGeneLog™. https://www.mygenelog.com/variants/rs112876941

← See all variants