Standard

MICB or MICA protein levels

near RN7SKP186 · rs112865839

Where this position leads

Condition: Celiac Disease

rs112865839 Condition: Celiac Disease Celiac Disease Condition rs112865839 rs112865839 near RN7SKP1…

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.34 lower (95% confidence interval 0.28-0.4); p = 1 × 10−47.

How common The T allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 6, band 6p21.33 — between genes, 7.7 kb from RN7SKP186.

What each result means

C/C No copy of the version the research linked to MICB or MICA protein levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to MICB or MICA protein levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to MICB or MICA protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs112865839

What is rs112865839?

rs112865839 is a single position in the genome, in or near the near RN7SKP186 gene. Published research associates it with micb or mica protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs112865839 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs112865839 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs112865839 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

MICB or MICA protein levels (rs112865839). MyGeneLog™. https://www.mygenelog.com/variants/rs112865839

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