Standard

Ewing sarcoma

LINC00237 · rs112837127

Where this position leads

Condition: Ewing Sarcoma

rs112837127 Condition: Ewing Sarcoma Ewing Sarcoma Condition rs112837127 rs112837127 LINC00237

What the study found

Who was studied 733 European ancestry cases, 1,346 European ancestry controls.

The effect Each copy of the A allele carried 0.19 times the odds of Ewing sarcoma (95% confidence interval 0.08-0.37); p = 7 × 10−9.

How common The A allele had a frequency of about 3% in the people studied.

Where it sits Chromosome 20, band 20p11.23 — inside LINC00237.

What each result means

A/A Two copies of the version the research linked to Ewing sarcoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Ewing sarcoma. That is a smaller link than two copies.
G/G No copy of the version the research linked to Ewing sarcoma. This is the starting point the study compared everyone against.
Source

Questions about rs112837127

What is rs112837127?

rs112837127 is a single position in the genome, in or near the LINC00237 gene. Published research associates it with ewing sarcoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs112837127 linked to?

On MyGeneLog this position is linked to Ewing Sarcoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs112837127 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs112837127 come from?

GWAS Catalog, PloS one 2020, PMID:32881892. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Ewing sarcoma (rs112837127). MyGeneLog™. https://www.mygenelog.com/variants/rs112837127

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