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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 340,567 European ancestry individuals, 5,974 African ancestry individuals, 7,283 South Asian ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.0393 lower (95% confidence interval 0.027-0.052); p = 2 × 10−9.
Where it sits Chromosome 15, band 15q22.2 — in an intron of VPS13C.
What each result means
C/CTwo copies of the version the research linked to Insulin-like growth factor 1 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Insulin-like growth factor 1 levels. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Insulin-like growth factor 1 levels. This is the starting point the study compared everyone against.
Nature genetics · 2021 · PMID 33462484 · open access
Questions about rs112732813
What is rs112732813?
rs112732813 is a single position in the genome, in or near the VPS13C gene. Published research associates it with insulin-like growth factor 1 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs112732813 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs112732813 come from?
GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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