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What is your height? (cm, inv-normal transformed)

near TMEM270 · rs112691514

Where this position leads

Condition: Height

rs112691514 Condition: Height Height Condition rs112691514 rs112691514 near TMEM270

What the study found

Who was studied 51,137 African American or Afro-Caribbean individuals, 27,055 Hispanic or Latin American individuals, 3,110 East Asian ancestry individuals, 283,251 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0492 higher (95% confidence interval 0.038-0.061); p = 5 × 10−17.

How common The G allele had a frequency of about 87% in the people studied.

Where it sits Chromosome 7, band 7q11.23 — between genes, 23.9 kb from TMEM270.

What each result means

C/C No copy of the version the research linked to What is your height? (cm, inv-normal transformed). This is the starting point the study compared everyone against.
C/G One copy of the version the research linked to What is your height? (cm, inv-normal transformed). That is a smaller link than two copies.
G/G Two copies of the version the research linked to What is your height? (cm, inv-normal transformed). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source
Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program
Verma A, Huffman JE, Rodriguez A, Conery M, Liu M, Ho YL, Kim Y, Heise DA, Guare L, Panickan VA, Garcon H, Linares F
and 59 more — show all
Costa L, Goethert I, Tipton R, Honerlaw J, Davies L, Whitbourne S, Cohen J, Posner DC, Sangar R, Murray M, Wang X, Dochtermann DR, Devineni P, Shi Y, Nandi TN, Assimes TL, Brunette CA, Carroll RJ, Clifford R, Duvall S, Gelernter J, Hung A, Iyengar SK, Joseph J, Kember R, Kranzler H, Kripke CM, Levey D, Luoh SW, Merritt VC, Overstreet C, Deak JD, Grant SFA, Polimanti R, Roussos P, Shakt G, Sun YV, Tsao N, Venkatesh S, Voloudakis G, Justice A, Begoli E, Ramoni R, Tourassi G, Pyarajan S, Tsao P, O'Donnell CJ, Muralidhar S, Moser J, Casas JP, Bick AG, Zhou W, Cai T, Voight BF, Cho K, Gaziano JM, Madduri RK, Damrauer S, Liao KP
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access

Questions about rs112691514

What is rs112691514?

rs112691514 is a single position in the genome, in or near the near TMEM270 gene. Published research associates it with what is your height? (cm, inv-normal transformed). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs112691514 linked to?

On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.

Does having rs112691514 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs112691514 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

What is your height? (cm, inv-normal transformed) (rs112691514). MyGeneLog™. https://www.mygenelog.com/variants/rs112691514

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