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C-reactive protein levels

near OR10AE1P · rs112689575

Where this position leads

Condition: C-Reactive Protein Levels

rs112689575 Condition: C-Reactive Protein Levels C-Reactive Protein Levels Condition rs112689575 rs112689575 near OR10AE1P

What the study found

Who was studied 418,642 British ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.052 lower (95% confidence interval 0.038-0.066); p = 5 × 10−13.

How common The G allele had a frequency of about 98% in the people studied.

Where it sits Chromosome 1, band 1q23.2 — between genes, 0.4 kb from OR10AE1P.

What each result means

A/A No copy of the version the research linked to C-reactive protein levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to C-reactive protein levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to C-reactive protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs112689575

What is rs112689575?

rs112689575 is a single position in the genome, in or near the near OR10AE1P gene. Published research associates it with c-reactive protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs112689575 linked to?

On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.

Does having rs112689575 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs112689575 come from?

GWAS Catalog, European journal of epidemiology 2020, PMID:31900758. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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C-reactive protein levels (rs112689575). MyGeneLog™. https://www.mygenelog.com/variants/rs112689575

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