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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 3,169 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.256 higher (95% confidence interval 0.2-0.31); p = 5 × 10−21.
How common The G allele had a frequency of about 15% in the people studied.
Where it sits Chromosome 1, band 1p33 — a missense change in CYP4A11.
What each result means
A/ANo copy of the version the research linked to Plasma X-24949 levels in chronic kidney disease. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Plasma X-24949 levels in chronic kidney disease. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Plasma X-24949 levels in chronic kidney disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2023 · PMID 37277652 · open access
Questions about rs1126742
What is rs1126742?
rs1126742 is a single position in the genome, in or near the CYP4A11 gene. Published research associates it with plasma x-24949 levels in chronic kidney disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs1126742 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1126742 come from?
GWAS Catalog, GWAS Catalog n.d., PMID:37277652. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Plasma X-24949 levels in chronic kidney disease (rs1126742). MyGeneLog™. https://www.mygenelog.com/variants/rs1126742