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Huntingtin-interacting protein 1-related protein protein levels (SomaScan ID:5487-7)

SLAMF7 · rs11265473

What the study found

Who was studied 197 Shetland Isles origin ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.936 lower (95% confidence interval 0.84-1.03); p = 3 × 10−20.

Where it sits Chromosome 1, band 1q23.3 — in the 3′ untranslated region of SLAMF7.

What each result means

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Huntingtin-interacting protein 1-related protein protein levels (SomaScan ID:5487-7) compared to the general population.
G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Huntingtin-interacting protein 1-related protein protein levels (SomaScan ID:5487-7).
T/T Published research associates this genotype with typical/baseline likelihood of Huntingtin-interacting protein 1-related protein protein levels (SomaScan ID:5487-7) — no copies of the reported risk allele.
Source

Questions about rs11265473

What is rs11265473?

rs11265473 is a single position in the genome, in or near the SLAMF7 gene. Published research associates it with huntingtin-interacting protein 1-related protein protein levels (somascan id:5487-7). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11265473 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11265473 come from?

GWAS Catalog, Communications biology 2025, PMID:40883583. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Huntingtin-interacting protein 1-related protein protein levels (SomaScan ID:5487-7) (rs11265473). MyGeneLog™. https://www.mygenelog.com/variants/rs11265473

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