A/APublished research associates this genotype with typical/baseline likelihood of Ulcerative colitis — no copies of the reported risk allele. (GWAS Catalog, Nature 2012, PMID:23128233)
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Ulcerative colitis. (GWAS Catalog, Nature 2012, PMID:23128233)
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Ulcerative colitis compared to the general population. (GWAS Catalog, Nature 2012, PMID:23128233)
Source: GWAS Catalog, Nature 2012, PMID:23128233
Questions about rs1126510
What is rs1126510?
rs1126510 is a single position in the genome, in or near the CALM3 gene. Published research associates it with ulcerative colitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1126510 linked to?
On MyGeneLog this position is linked to Ulcerative Colitis. The research behind each link, and its sources, are set out on that condition page.
Does having rs1126510 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1126510 come from?
GWAS Catalog, Nature 2012, PMID:23128233. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.