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Probable serine carboxypeptidase CPVL levels

PEAR1 · rs11264581

What the study found

Who was studied 10,708 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.159 lower (95% confidence interval 0.13-0.19); p = 1 × 10−21.

How common The A allele had a frequency of about 19% in the people studied.

Where it sits Chromosome 1, band 1q23.1 — a missense change in PEAR1.

What each result means

A/A Two copies of the version the research linked to Probable serine carboxypeptidase CPVL levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Probable serine carboxypeptidase CPVL levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Probable serine carboxypeptidase CPVL levels. This is the starting point the study compared everyone against.
Source

Questions about rs11264581

What is rs11264581?

rs11264581 is a single position in the genome, in or near the PEAR1 gene. Published research associates it with probable serine carboxypeptidase cpvl levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11264581 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11264581 come from?

GWAS Catalog, Science (New York, N.Y.) 2021, PMID:34648354. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Probable serine carboxypeptidase CPVL levels (rs11264581). MyGeneLog™. https://www.mygenelog.com/variants/rs11264581

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