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Who was studied at least 60,620 European ancestry cases, at least 970,216 European ancestry controls (MTAG boosted by 455,258 Alzheimer's disease samples).
The effect
Each copy of the T allele shifted the measure 0.0208 higher (95% confidence interval 0.018-0.024); p = 7 × 10−37.
Where it sits Chromosome 1, band 1q21.3 — in an intron of KCNN3.
What each result means
C/CNo copy of the version the research linked to Atrial fibrillation (MTAG). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Atrial fibrillation (MTAG). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Atrial fibrillation (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2024 · PMID 39537608 · open access
Questions about rs11264273
What is rs11264273?
rs11264273 is a single position in the genome, in or near the KCNN3 gene. Published research associates it with atrial fibrillation (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11264273 linked to?
On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.
Does having rs11264273 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11264273 come from?
GWAS Catalog, Nature communications 2024, PMID:39537608. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 1611212Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others12Total16Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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