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Who was studied 2,277 African American cases, 3,098 East Asian ancestry cases, 3,704 European ancestry cases, 6,215 Hispanic/Latino cases, 2,939 South Asian ancestry cases, 2,283 African American controls, 2,921 East Asian ancestry controls, 3,514 European ancestry controls, 5,939 Hispanic/Latino controls, 3,022 South Asian ancestry controls.
The effect
The reported allele is T; the catalogue records no effect size
; p = 6 × 10−17.
How common The T allele had a frequency of about 31% in the people studied.
Where it sits Chromosome 10, band 10p13 — in an intron of CDC123.
What each result means
G/GNo copy of the version the research linked to Type 2 diabetes. This is the starting point the study compared everyone against.
G/TOne copy of the version the research linked to Type 2 diabetes. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Type 2 diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs11257600 is a single position in the genome, in or near the CDC123 gene. Published research associates it with type 2 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11257600 linked to?
On MyGeneLog this position is linked to Type 2 Diabetes. The research behind each link, and its sources, are set out on that condition page.
Does having rs11257600 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11257600 come from?
GWAS Catalog, Nature 2019, PMID:31118516. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Type 2 diabetes (rs11257600). MyGeneLog™. https://www.mygenelog.com/variants/rs11257600