Sensitive

Metabolic dysfunction-associated steatotic liver disease (MTAG)

LINC02702 · rs1124874

Where this position leads

Condition: Nonalcoholic Fatty Liver Disease (NAFLD)

rs1124874 Condition: Nonalcoholic Fatty Liver Disease (NAFLD) Nonalcoholic Fatty Liver Disease (NAFLD) Condition rs1124874 rs1124874 LINC02702

What the study found

Who was studied 122,644 European ancestry individuals (MTAG effective sample size boosted by proton density fat fraction samples).

The effect Each copy of the G allele shifted the measure 0.0682 higher (95% confidence interval 0.052-0.085); p = 2 × 10−16.

How common The G allele had a frequency of about 92% in the people studied.

Where it sits Chromosome 11, band 11q23.3 — in an intron of LINC02702.

What each result means

A/A No copy of the version the research linked to Metabolic dysfunction-associated steatotic liver disease (MTAG). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Metabolic dysfunction-associated steatotic liver disease (MTAG). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Metabolic dysfunction-associated steatotic liver disease (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs1124874

What is rs1124874?

rs1124874 is a single position in the genome, in or near the LINC02702 gene. Published research associates it with metabolic dysfunction-associated steatotic liver disease (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1124874 linked to?

On MyGeneLog this position is linked to Nonalcoholic Fatty Liver Disease (NAFLD). The research behind each link, and its sources, are set out on that condition page.

Does having rs1124874 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1124874 come from?

GWAS Catalog, Science advances 2026, PMID:41686896. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Metabolic dysfunction-associated steatotic liver disease (MTAG) (rs1124874). MyGeneLog™. https://www.mygenelog.com/variants/rs1124874

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