Sensitive

Thyroid cancer

BET1L · rs11245983

Where this position leads

Condition: Thyroid Cancer

rs11245983 Condition: Thyroid Cancer Thyroid Cancer Condition rs11245983 rs11245983 BET1L

What the study found

Who was studied 6,056 European ancestry cases, 907,977 European ancestry controls, 4,661 East Asian ancestry cases, 354,129 East Asian ancestry controls, 5,450 African, Admixed American, European, East Asian, South Asian or unknown ancestry cases, 1,168,268 African, Admixed American, European, East Asian, South Asian or unknown ancestry controls.

The effect Each copy of the A allele shifted the measure 0.362 lower (95% confidence interval 0.29-0.44); p = 2 × 10−20.

Where it sits Chromosome 11, band 11p15.5 — inside BET1L.

What each result means

A/A Two copies of the version the research linked to Thyroid cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Thyroid cancer. That is a smaller link than two copies.
G/G No copy of the version the research linked to Thyroid cancer. This is the starting point the study compared everyone against.
Source

Questions about rs11245983

What is rs11245983?

rs11245983 is a single position in the genome, in or near the BET1L gene. Published research associates it with thyroid cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11245983 linked to?

On MyGeneLog this position is linked to Thyroid Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs11245983 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11245983 come from?

GWAS Catalog, Nature communications 2026, PMID:42431967. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Thyroid cancer (rs11245983). MyGeneLog™. https://www.mygenelog.com/variants/rs11245983

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