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Disintegrin and metalloproteinase domain-containing protein 12 levels

ADAM12 · rs11244958

What the study found

Who was studied 3,506 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.293 lower (95% confidence interval 0.25-0.34); p = 4 × 10−38.

How common The G allele had a frequency of about 48% in the people studied.

Where it sits Chromosome 10, band 10q26.2 — in an intron of ADAM12.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Disintegrin and metalloproteinase domain-containing protein 12 levels — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Disintegrin and metalloproteinase domain-containing protein 12 levels.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Disintegrin and metalloproteinase domain-containing protein 12 levels compared to the general population.
Source

Questions about rs11244958

What is rs11244958?

rs11244958 is a single position in the genome, in or near the ADAM12 gene. Published research associates it with disintegrin and metalloproteinase domain-containing protein 12 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11244958 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11244958 come from?

GWAS Catalog, Nature genetics 2024, PMID:39528825. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Disintegrin and metalloproteinase domain-containing protein 12 levels (rs11244958). MyGeneLog™. https://www.mygenelog.com/variants/rs11244958

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