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Linoleic acid levels

MARCHF8 · rs11239569

What the study found

Who was studied 114,999 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.03 lower (95% confidence interval 0.021-0.039); p = 3 × 10−10.

How common The C allele had a frequency of about 75% in the people studied.

Where it sits Chromosome 10, band 10q11.22 — in an intron of MARCHF8.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Linoleic acid levels — no copies of the reported risk allele.
A/C Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Linoleic acid levels.
C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Linoleic acid levels compared to the general population.
Source

Questions about rs11239569

What is rs11239569?

rs11239569 is a single position in the genome, in or near the MARCHF8 gene. Published research associates it with linoleic acid levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11239569 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11239569 come from?

GWAS Catalog, BMC medicine 2022, PMID:35692035. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Linoleic acid levels (rs11239569). MyGeneLog™. https://www.mygenelog.com/variants/rs11239569

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