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Who was studied 24,167 European ancestry individuals; replicated in 9,456 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0 fl lower (95% confidence interval 0.002-0.003); p = 1 × 10−10.
Where it sits Chromosome 10, band 10q11.22 — in an intron of MARCHF8.
What each result means
A/ANo copy of the version the research linked to Mean corpuscular volume. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Mean corpuscular volume. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Mean corpuscular volume. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2009 · PMID 19862010 · open access
Questions about rs11239550
What is rs11239550?
rs11239550 is a single position in the genome, in or near the MARCH8 gene. Published research associates it with mean corpuscular volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11239550 linked to?
On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.
Does having rs11239550 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11239550 come from?
GWAS Catalog, Nat Genet 2009, PMID:19862010. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
3 423213224223Reads by AI crawlersClaude3ChatGPT2Google · Gemini0Perplexity1Meta AI3Microsoft · Copilot2Amazon2Apple4China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others23Total42Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Mean corpuscular volume (rs11239550). MyGeneLog™. https://www.mygenelog.com/variants/rs11239550