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Coronary dominance (left dominant vs right dominant)

near LINC03089 · rs11238908

What the study found

Who was studied 4,944 European ancestry left dominant individuals, 37,613 European ancestry right dominant individuals, 1,167 Sub-Saharan African ancestry left dominant individuals, 8,280 Sub-Saharan African ancestry right dominant individuals, 437 Hispanic or Latin American left dominant individuals, 3,717 Hispanic or Latin American right dominant individuals, 24 East Asian ancestry left dominant individuals, 287 East Asian ancestry right dominant individuals, 6 South Asian ancestry left dominant individuals, 25 South Asian ancestry right dominant individuals, 62 left dominant individuals, 483 right dominant individuals.

The effect Each copy of the G allele carried 1.29 times the odds of Coronary dominance (left dominant vs right dominant) (95% confidence interval 1.22-1.36); p = 7 × 10−21.

How common The G allele had a frequency of about 12% in the people studied.

Where it sits Chromosome 10, band 10q11.21 — between genes, 67 kb from LINC03089.

What each result means

G/G Two copies of the version the research linked to Coronary dominance (left dominant vs right dominant). That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Coronary dominance (left dominant vs right dominant). That is a smaller link than two copies.
T/T No copy of the version the research linked to Coronary dominance (left dominant vs right dominant). This is the starting point the study compared everyone against.
Source

Questions about rs11238908

What is rs11238908?

rs11238908 is a single position in the genome, in or near the near LINC03089 gene. Published research associates it with coronary dominance (left dominant vs right dominant). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11238908 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11238908 come from?

GWAS Catalog, Cell 2025, PMID:40049164. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Coronary dominance (left dominant vs right dominant) (rs11238908). MyGeneLog™. https://www.mygenelog.com/variants/rs11238908

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