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Insomnia

PDE2A · rs11235550

Where this position leads

Condition: Insomnia

rs11235550 Condition: Insomnia Insomnia Condition rs11235550 rs11235550 PDE2A

What the study found

Who was studied 593,724 European ancestry cases, 1,771,286 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.015 lower (95% confidence interval 0.011-0.019); p = 4 × 10−13.

Where it sits Chromosome 11, band 11q13.4 — in an intron of PDE2A.

What each result means

C/C No copy of the version the research linked to Insomnia. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Insomnia. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Insomnia. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11235550

What is rs11235550?

rs11235550 is a single position in the genome, in or near the PDE2A gene. Published research associates it with insomnia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11235550 linked to?

On MyGeneLog this position is linked to Insomnia. The research behind each link, and its sources, are set out on that condition page.

Does having rs11235550 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11235550 come from?

GWAS Catalog, Nature genetics 2022, PMID:35835914. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Insomnia (rs11235550). MyGeneLog™. https://www.mygenelog.com/variants/rs11235550

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