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Tryptase beta-1 levels

near TPSAB1 · rs112332886

What the study found

Who was studied 3,506 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 1.17 higher (95% confidence interval 1.1-1.24); p = 6 × 10−209.

How common The A allele had a frequency of about 10% in the people studied.

Where it sits Chromosome 16, band 16p13.3 — between genes, 0.7 kb from TPSAB1.

What each result means

A/A Two copies of the version the research linked to Tryptase beta-1 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Tryptase beta-1 levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Tryptase beta-1 levels. This is the starting point the study compared everyone against.
Source

Questions about rs112332886

What is rs112332886?

rs112332886 is a single position in the genome, in or near the near TPSAB1 gene. Published research associates it with tryptase beta-1 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs112332886 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs112332886 come from?

GWAS Catalog, Nature genetics 2024, PMID:39528825. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Tryptase beta-1 levels (rs112332886). MyGeneLog™. https://www.mygenelog.com/variants/rs112332886

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