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Skin pigmentation (conditioned on rs1426654 and rs35397)

MFSD12 · rs112332856

What the study found

Who was studied 1,047 Hispanic/Latin American individuals, 684 Cape Verdian individuals, 373 African American individuals.

The effect Each copy of the C allele shifted the measure 0.197 higher (95% confidence interval 0.13-0.27); p = 2 × 10−8.

Where it sits Chromosome 19, band 19p13.3 — inside MFSD12.

What each result means

C/C Two copies of the version the research linked to Skin pigmentation (conditioned on rs1426654 and rs35397). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Skin pigmentation (conditioned on rs1426654 and rs35397). That is a smaller link than two copies.
T/T No copy of the version the research linked to Skin pigmentation (conditioned on rs1426654 and rs35397). This is the starting point the study compared everyone against.
Source

Questions about rs112332856

What is rs112332856?

rs112332856 is a single position in the genome, in or near the MFSD12 gene. Published research associates it with skin pigmentation (conditioned on rs1426654 and rs35397). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs112332856 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs112332856 come from?

GWAS Catalog, BMC Genet 2019, PMID:31315583. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Skin pigmentation (conditioned on rs1426654 and rs35397) (rs112332856). MyGeneLog™. https://www.mygenelog.com/variants/rs112332856

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