Standard
Glioblastoma
near FAM181B · rs11233250
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Glioblastoma compared to the general population.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Glioblastoma.
T/T
Published research associates this genotype with typical/baseline likelihood of Glioblastoma — no copies of the reported risk allele.
Source
Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors
Melin BS,
Barnholtz-Sloan JS,
Wrensch MR,
Johansen C,
Il'yasova D,
Kinnersley B,
Ostrom QT,
Labreche K,
Chen Y,
Armstrong G,
Liu Y,
Eckel-Passow JE
and 51 more — show all
Decker PA,
Labussière M,
Idbaih A,
Hoang-Xuan K,
Di Stefano AL,
Mokhtari K,
Delattre JY,
Broderick P,
Galan P,
Gousias K,
Schramm J,
Schoemaker MJ,
Fleming SJ,
Herms S,
Heilmann S,
Nöthen MM,
Wichmann HE,
Schreiber S,
Swerdlow A,
Lathrop M,
Simon M,
Sanson M,
Andersson U,
Rajaraman P,
Chanock S,
Linet M,
Wang Z,
Yeager M,
Wiencke JK,
Hansen H,
McCoy L,
Rice T,
Kosel ML,
Sicotte H,
Amos CI,
Bernstein JL,
Davis F,
Lachance D,
Lau C,
Merrell RT,
Shildkraut J,
Ali-Osman F,
Sadetzki S,
Scheurer M,
Shete S,
Lai RK,
Claus EB,
Olson SH,
Jenkins RB,
Houlston RS,
Bondy ML
Nature genetics · 2017 · PMID 28346443
Questions about rs11233250
What is rs11233250?
rs11233250 is a single position in the genome, in or near the near FAM181B gene. Published research associates it with glioblastoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs11233250 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11233250 come from?
GWAS Catalog, Nat Genet 2017, PMID:28346443. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants