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Who was studied 390,751 European ancestry female cases, 1,018,386 European ancestry female controls.
The effect
Each copy of the A allele shifted the measure 0.014 lower (95% confidence interval 0.01-0.018); p = 4 × 10−11.
Where it sits Chromosome 10, band 10q24.32 — in an intron of CNNM2.
What each result means
A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Insomnia compared to the general population.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Insomnia.
G/GPublished research associates this genotype with typical/baseline likelihood of Insomnia — no copies of the reported risk allele.
rs112314091 is a single position in the genome, in or near the CNNM2 gene. Published research associates it with insomnia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs112314091 linked to?
On MyGeneLog this position is linked to Insomnia. The research behind each link, and its sources, are set out on that condition page.
Does having rs112314091 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs112314091 come from?
GWAS Catalog, Nature genetics 2022, PMID:35835914. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 00Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0Others0Total0Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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