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Free Cholesterol to Cholesteryl Esters in Large HDL ratio

near CCL26 · rs112299229

What the study found

Who was studied 98,316 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.033 higher (95% confidence interval 0.022-0.044); p = 2 × 10−9.

How common The T allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 7, band 7q11.23 — between genes, 10.1 kb from CCL26.

What each result means

C/C No copy of the version the research linked to Free Cholesterol to Cholesteryl Esters in Large HDL ratio. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Free Cholesterol to Cholesteryl Esters in Large HDL ratio. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Free Cholesterol to Cholesteryl Esters in Large HDL ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs112299229

What is rs112299229?

rs112299229 is a single position in the genome, in or near the near CCL26 gene. Published research associates it with free cholesterol to cholesteryl esters in large hdl ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs112299229 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs112299229 come from?

GWAS Catalog, Ophthalmology science 2024, PMID:39091897. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Free Cholesterol to Cholesteryl Esters in Large HDL ratio (rs112299229). MyGeneLog™. https://www.mygenelog.com/variants/rs112299229

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