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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 462,690 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.033 lower (95% confidence interval 0.023-0.043); p = 4 × 10−11.
How common The G allele had a frequency of about 96% in the people studied.
Where it sits Chromosome 11, band 11p11.2 — in an intron of HARBI1.
What each result means
A/APublished research associates this genotype with typical/baseline likelihood of Lifetime smoking index — no copies of the reported risk allele.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Lifetime smoking index.
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Lifetime smoking index compared to the general population.
Psychological medicine · 2020 · PMID 31689377 · open access
Questions about rs112282219
What is rs112282219?
rs112282219 is a single position in the genome, in or near the HARBI1 gene. Published research associates it with lifetime smoking index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs112282219 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs112282219 come from?
GWAS Catalog, Psychological medicine 2020, PMID:31689377. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Lifetime smoking index (rs112282219). MyGeneLog™. https://www.mygenelog.com/variants/rs112282219