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Who was studied 312,888 European ancestry individuals, 5,568 African ancestry individuals, 6,685 South Asian ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0195 lower (95% confidence interval 0.013-0.026); p = 9 × 10−10.
Where it sits Chromosome 11, band 11q13.1 — in an intron of CFL1.
What each result means
A/ANo copy of the version the research linked to Serum phosphate levels. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Serum phosphate levels. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Serum phosphate levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2021 · PMID 33462484 · open access
Questions about rs11227332
What is rs11227332?
rs11227332 is a single position in the genome, in or near the CFL1 gene. Published research associates it with serum phosphate levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs11227332 linked to?
On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.
Does having rs11227332 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11227332 come from?
GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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