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Matrix metalloproteinase levels

MMP-1 · rs11225434

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Matrix metalloproteinase levels compared to the general population. (GWAS Catalog, Circ Cardiovasc Genet 2009, PMID:20031604)
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Matrix metalloproteinase levels. (GWAS Catalog, Circ Cardiovasc Genet 2009, PMID:20031604)
T/T Published research associates this genotype with typical/baseline likelihood of Matrix metalloproteinase levels — no copies of the reported risk allele. (GWAS Catalog, Circ Cardiovasc Genet 2009, PMID:20031604)

Source: GWAS Catalog, Circ Cardiovasc Genet 2009, PMID:20031604

Questions about rs11225434

What is rs11225434?

rs11225434 is a single position in the genome, in or near the MMP-1 gene. Published research associates it with matrix metalloproteinase levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11225434 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11225434 come from?

GWAS Catalog, Circ Cardiovasc Genet 2009, PMID:20031604. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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