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Sleep duration

ERC2 · rs112230981

Where this position leads

Condition: Sleep and Circadian Rhythm

rs112230981 Condition: Sleep and Circadian Rhythm Sleep and Circadian Rhythm Condition rs112230981 rs112230981 ERC2

What the study found

Who was studied 7,288 African ancestry individuals, 7,485 South Asian ancestry individuals, 8,726 Hispanic or Latin American individuals, 446,118 European ancestry individuals, 13,618 East Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0312 hrs higher (95% confidence interval 0.021-0.041); p = 2 × 10−9.

Where it sits Chromosome 3, band 3p14.3 — in an intron of ERC2.

What each result means

A/A Two copies of the version the research linked to Sleep duration. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Sleep duration. That is a smaller link than two copies.
G/G No copy of the version the research linked to Sleep duration. This is the starting point the study compared everyone against.
Source

Questions about rs112230981

What is rs112230981?

rs112230981 is a single position in the genome, in or near the ERC2 gene. Published research associates it with sleep duration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs112230981 linked to?

On MyGeneLog this position is linked to Sleep and Circadian Rhythm. The research behind each link, and its sources, are set out on that condition page.

Does having rs112230981 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs112230981 come from?

GWAS Catalog, Human molecular genetics 2023, PMID:37384397. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Sleep duration (rs112230981). MyGeneLog™. https://www.mygenelog.com/variants/rs112230981

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