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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 11,138 Chinese ancestry cases, 85,294 Chinese ancestry controls.
The effect
Each copy of the C allele carried 0.83 times the odds of Gestational thrombocytopenia (95% confidence interval 0.79-0.87); p = 2 × 10−13.
How common The C allele had a frequency of about 36% in the people studied.
Where it sits Chromosome 11, band 11q24.2 — in an intron of ST3GAL4.
What each result means
C/CTwo copies of the version the research linked to Gestational thrombocytopenia. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Gestational thrombocytopenia. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Gestational thrombocytopenia. This is the starting point the study compared everyone against.
rs11220476 is a single position in the genome, in or near the ST3GAL4 gene. Published research associates it with gestational thrombocytopenia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs11220476 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs11220476 come from?
GWAS Catalog, Blood 2024, PMID:38064665. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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