Standard

LDL cholesterol

ST3GAL4 · rs11220462

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of LDL cholesterol compared to the general population. (GWAS Catalog, Nature 2010, PMID:20686565)

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with LDL cholesterol. (GWAS Catalog, Nature 2010, PMID:20686565)

G/G Published research associates this genotype with typical/baseline likelihood of LDL cholesterol — no copies of the reported risk allele. (GWAS Catalog, Nature 2010, PMID:20686565)

Source: GWAS Catalog, Nature 2010, PMID:20686565

Questions about rs11220462

What is rs11220462?

rs11220462 is a single position in the genome, in or near the ST3GAL4 gene. Published research associates it with ldl cholesterol. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs11220462 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11220462 come from?

GWAS Catalog, Nature 2010, PMID:20686565. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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