Standard

Mean corpuscular hemoglobin concentration

near HSPA8 · rs11218946

Where this position leads

Condition: Blood Cell Counts

rs11218946 Condition: Blood Cell Counts Blood Cell Counts Condition rs11218946 rs11218946 near HSPA8

What the study found

Who was studied 135,482 East Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0453 lower (95% confidence interval 0.038-0.053); p = 7 × 10−32.

How common The G allele had a frequency of about 32% in the people studied.

Where it sits Chromosome 11, band 11q24.1 — between genes, 2.5 kb from HSPA8.

What each result means

A/A No copy of the version the research linked to Mean corpuscular hemoglobin concentration. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Mean corpuscular hemoglobin concentration. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Mean corpuscular hemoglobin concentration. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs11218946

What is rs11218946?

rs11218946 is a single position in the genome, in or near the near HSPA8 gene. Published research associates it with mean corpuscular hemoglobin concentration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs11218946 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs11218946 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs11218946 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Mean corpuscular hemoglobin concentration (rs11218946). MyGeneLog™. https://www.mygenelog.com/variants/rs11218946

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