0 10217Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others7Total10Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 15,771 East Asian ancestry cases, 178,777 East Asian ancestry controls, 170,756 European ancestry cases, 329,443 European ancestry controls.
The effect
Each copy of the A allele shifted the measure 0.0164 lower (95% confidence interval 0.011-0.022); p = 4 × 10−8.
How common The A allele had a frequency of about 6% in the people studied.
Where it sits Chromosome 2, band 2p16.1 — in an intron of VRK2.
What each result means
A/ATwo copies of the version the research linked to Depression. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Depression. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Depression. This is the starting point the study compared everyone against.
JAMA psychiatry · 2021 · PMID 34586374 · open access
Questions about rs112176860
What is rs112176860?
rs112176860 is a single position in the genome, in or near the VRK2 gene. Published research associates it with depression. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs112176860 linked to?
On MyGeneLog this position is linked to Endometriosis and Depression: Shared Genetics. The research behind each link, and its sources, are set out on that condition page.
Does having rs112176860 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs112176860 come from?
GWAS Catalog, JAMA psychiatry 2021, PMID:34586374. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 10217Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others7Total10Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.